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Rev. chil. nutr ; 38(1): 15-21, mar. 2011. tab
Article in Spanish | LILACS | ID: lil-592071

ABSTRACT

A case-control study was carried out in order to analyze the association between diet and risk of non melanoma skin cancer -basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), with adjustments for demographic, anthropometric and phenotypic characteristics, sunburns history, skin cancerfamily history, sun-exposure history and skin sensitivity to sun exposure. A full-body skin examination was performed. Dietary data were obtained applying a standardized semi-quantitative questionnaire of consumption frequency. Cases (n=27; age: 65,5+15,1 years) and controls (n=37; age: 63,9+12,3 years) were attended at the same facilities. A decreased risk ofBCC and SCC tumors (Adjusted Odd Ratio=0.10; IC 95 percent= 0.02-0.63; p=0.01) was found for high intakes of green leafy vegetables (more than 40 gr/day). However, results obtained for fruits, cruciferous, vitamin A and carotene-rich vegetables and other vegetables were not statistically significant.


Mediante un diseño de casos y controles se evaluó si la dieta habitual modifica el riesgo de desarrollar cáncer de piel no melanoma: carcinomas basocelulares y carcinomas espinocelulares. En la consulta se consignaron datos demográficos, características fenotípicas y antropométricas, antecedentes de quemadura solar, antecedentes familiares de cáncer de piel y hábitos de exposición solar, y se realizó un exhaustivo examen físico cutáneo. La dieta fue evaluada por cuestionarios semi-cuantitativos de frecuencia de consumo. Se estudiaron 27 casos (edad: 65,5±15,1 años) y 37 controles (63,9±12,3) que asistieron a las mismas instituciones por otras patologías. La ingesta alta de vegetales de hojas verdes (más de 40 g/d) actuaría como factor protector (Odd Ratio ajustado= 0,10; IC 95 por ciento= 0,02-0,63; p=0,01), modificando el efecto negativo de la exposición solar. En cambio, los resultados obtenidos para frutas, crucíferas, vegetales ricos en vitamina A y carotenos y otros vegetales no resultaron estadísticamente significativos.


Subject(s)
Humans , Male , Female , Carcinoma, Basal Cell/prevention & control , Carcinoma, Squamous Cell/prevention & control , Feeding Behavior , Skin Neoplasms/diet therapy , Skin Neoplasms/epidemiology , Skin Neoplasms/prevention & control , Ascorbic Acid/therapeutic use , Folic Acid/therapeutic use , Lutein/therapeutic use , Risk Factors , Sunburn , Vitamin E/therapeutic use
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